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67. Angew. Chem. Int. Ed., 2017, Accepted Article, Selective Reductive Elimination at Alkyl Pd(IV) via Dissociative Ligand Ionization Enables Catalytic C(sp3)—H Amination to Azetidines

66. Chem. Sci., 2017, 8, 8198, The α-tertiary amine motif drives remarkable selectivity for Pd-catalyzed carbonylation of β-methylene C–H bonds

65. Angew. Chem. Int. Ed., 2017, 56, 11958, Selective Palladium(II)-Catalyzed Carbonylation of Methylene β-C−H Bonds in Aliphatic Amines

64. J. Am. Chem. Soc., 2017, 139, 9160, Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts

63. Chem. Sci., 2017, 8, 3586, Ligand-assisted palladium-catalyzed CH alkenylation of aliphatic amines for the synthesis of functionalized pyrrolidines

62. Chem. Sci., 2017, 8, 2588, Cobalt-catalysed CH carbonylative cyclisation of aliphatic amides

61. J. Am. Chem. Soc., 2017, 139, 1412, Palladium-Catalyzed Enantioselective C−H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

60. Science, 2016, 354, 851, A General Catalytic β-C−H Carbonylation of Aliphatic Amines to β-Lactams

59. J. Am. Chem. Soc., 2016, 138, 13183, Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts towards the Synthesis of P-Chiral Phosphines

58. Angew. Chem. Int. Ed., 2016, 128, 9024, Continuous-Flow Synthesis and Derivitization of Aziridines through Palladium-Catalyzed C(sp3)-H Activation

57. Chem. Sci., 2016, 7, 2706, The Total Synthesis of K-252c (Staurosporinone) via a Sequential C-H Functionalisation Strategy

56. Synlett, 2016, 27, 116, Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomitazation Strategy

55. Angew. Chem. Int. Ed., 2015, 54, 15840, Ligand-Enabled Catalytic C-H Arylation of Aliphatic Amines by a Four-Membered Ring Cyclopalladation Pathway

54. Nature Chem., 2015, 7, 1009, A Steric Tethering Approach Enables Palladium-Catalysed C-H Activation of Primary Amino Alcohols

53. J. Am. Chem. Soc., 2015, 137, 10632, Mechanistic Insights into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C-H Activation

52. J. Am. Chem. Soc., 2015, 137, 7986, Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts

51. Angew. Chem. Int. Ed., 2015, 54, 7857, Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional syn-1,3-Diol Derivatives

50. Angew. Chem. Int. Ed., 2015, 54, 5451, A Concise and Scalable Strategy for the Total Synthesis of Dictyodendrin B Based on Sequential C-H Functionalization

49. Chem. Sci., 2015, 6, 1277, A Counterion Triggered Arylation Strategy Using Diaryliodonium Fluorides

48. Angew. Chem. Int. Ed., 2014, 53, 13498, Gram-Scale Enantioselective Formal Synthesis of Morphine through an ortho-para Oxidative Phenolic Coupling Strategy

47. J. Am. Chem. Soc., 2014, 136, 8851, Cu-Catalyzed Cascades to Carbocycles: Union of Diaryliodonium Salts with Alkenes or Alkynes Exploiting Remote Carbocations

46. Nature, 2014, 510, 129, Palladium-catalysed C-H activation of aliphatic amines to give strained nitrogen heterocycles

45. J. Am. Chem. Soc., 2013, 135, 12532, Copper-catalyzed Carboarylation of Alkynes via Vinyl Cations

44. Angew. Chem. Int. Ed., 2013, 52, 9284, Copper-catalyzed Intramolecular Electrophilic Carbofunctionalisation of Allylic Amides

43. Angew. Chem. Int. Ed., 2013, 52, 5799, Copper-catalyzed Arylative Meyer-Schuster Rearrangement of Propargylic Alcohols to Complex Enones using Diaryliodonium Salts

42. J. Am. Chem. Soc., 2013, 135, 5332, Copper-catalyzed Electrophilic Carbofunctionalization of Alkynes to Highly Functionalized Tetrasubstituted Alkenes

41. J. Am. Chem. Soc., 2013, 135, 3772, Organocatalytic C-H bond Arylation of Aldehydes to Bis-heteroaryl Ketones

40. Angew. Chem. Int. Ed., 2012, 51, 9288, Chemical Synthesis of Aspidosperma Alkaloids inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products

39. J. Am. Chem. Soc., 2012, 134, 10773, Copper-catalyzed Alkene Arylation with Diaryliodonium Salts

38. J. Am. Chem. Soc., 2011, 50, 13778, Enantioselective alpha-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts

37. Chem. Sci., 2011, 2, 1487, Catalytic enantioselective assembly of complex molecules containing embedded quaternary stereogenic centres from simple anisidine derivatives

36. Chem. Soc. Rev., 2011, 40, 1885, Recent development in natural product synthesis using metal-catalysed C-H bond functionalisation

35. Angew. Chem. Int. Ed., 2011, 50, 1076, Palladium(II)-Catalyzed C-H Bond Arylation of Electron-Deficient Arenes at Room Temperature

34. Angew. Chem. Int. Ed., 2011, 50, 458, A Highly Para-Selective Copper(II)-Catalyzed Direct Arylation of Aniline and Phenol Derivatives

33. Angew. Chem. Int. Ed., 2011, 50, 463, Copper(II)-Catalyzed meta-Selective Direct Arylation of α-Aryl Carbonyl Compounds

32. Chem. Sci., 2011, Advance Article, Amine directed Pd(II)-catalyzed CH bond functionalization under ambient conditions

31. Tetrahedron., 2010, 66, 6429, (invited submission for Tetrahedron Award, Symposium-in-print: Professor Steven V. Ley) Alkynes to (E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions

30. Science, 2009, 323, 1593, A Meta-Selective Copper-Catalyzed CH Bond Arylation

This paper was featured in:

Perspectives in Science:Copper Puts Arenes in a Hard Position

RSC Chemistry World:Copper catalysts give meta aromatics

Research Highlights in Nature Chemistry:Electrophilic arylation: Substitution success

Chemical and Engineering News:Dodging The Substitution Laws

Science News:Helping Molecules Reach Meta

Angewandte Chemie:Meta-Selective Transition-Metal Catalyzed Arene C-H Bond Functionalization

This paper was voted as one of the top 12 papers of 2009 by Chemical and Engineering News Chemical Year in Review 2009.

29. J. Am. Chem. Soc., 2008, 130, 16184, Oxidative Pd(II)-Catalyzed C-H Bond Amination to Carbazole at Ambient Temperature

28. J. Am. Chem. Soc., 2008, 130, 8172, Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

27. Angew. Chem. Int. Ed., 2008, 47, 3004, Synthesis of Rhazinicine by a Metal-Catalyzed C-H Bond Functionalization Strategy

26. J. Am. Chem. Soc., 2008, 130, 404, An Enantioselective Organocatalytic Oxidative Dearomatization Strategy

25. Chem. Rev., 2007, 107, 5596, Recent Developments in the Use of Catalytic Asymmetric Ammonium Enolates in Chemical Synthesis

24. Drug Discovery Today, 2007, 12, 8, Enantioselective Organocatalysis Review

23. Angew. Chem., Int. Ed., 2006, 45, 6024, Enantioselective Catalytic Intramolecular Cyclopropanation using Modified Cinchona Alkaloid Organocatalysts

22. J. Am. Chem. Soc., 2006, 128, 2528, Mild Aerobic Oxidative Palladium (II) Catalyzed C-H Bond Functionalization: Regioselective and Switchable C-H Alkenylation and Annulation of Pyrroles

21. Angew. Chem., Int. Ed., 2006, 45, 2116, Organocatalytic Sigmatropic Reactions: Development of a [2,3] Wittig Rearrangement through Secondary Amine Catalysis

20. Angew. Chem., Int. Ed., 2005, 44, 3125, Palladium-Catalyzed Intermolecular Alkenylation of Indoles via Solvent-Controlled Regioselective C-H Functionalization

19. Angew. Chem., Int. Ed., 2004, 43, 4641, Enantioselective Organocatalytic Cyclopropanation via Ammonium Ylides

18. Angew. Chem., Int. Ed., 2004, 43, 2681, An Intramolecular Organocatalytic Cyclopropanation Reaction

17. Angew. Chem. Int., Ed., 2003, 42, 828, Organic-Catalyst-Mediated Cyclopropanation Reaction

Postdoctoral Studies: Professor Steven Ley

16. J. Org. Chem., 2006, 7, 2715, Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems To Generate Protected 1,3-Dicarbonyl Compounds

15. Synlett, 2005, 13, 2031, Synthesis of the EF Fragment of Spongistatin 1

14. Angew. Chem., Int. Ed., 2005, 44, 5433, Total Synthesis of Spongistatin 1: Exploiting the Latent Pseudo-Symmetry

13. Org. Lett., 2003, 5, 4819, Synthesis of C-1-C-28 ABCD Unit of Spongistatin 1

12. Org. Lett., 2003, 5, 4815, A Practical and Efficient Synthesis of the C-16-C-28 Spiroketal Fragment (CD) of the Spongistatins

11. Org. Lett., 2003, 5, 1147, Addition of Dithiols to Bis-Ynones: Development of a Versatile Platform for the Synthesis of Polyketide Natural Products

10. Org. & Biomol. Chem., 2003, 1, 15, Development of β-Keto 1,3-Dithianes as Versatile Intermediates for Organic Synthesis

Postdoctoral Studies: Professor Amos Smith

9. J. Am. Chem. Soc., 2003, 125, 14435, Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Epoxides, Epichlorohydrin and Vinyl Epoxides: Efficient, Rapid and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis

8. J. Am. Chem. Soc., 2002, 124, 14516, Dithiane Additions to Vinyl Epoxides: Steric Control over SN2 and SN2' Manifolds

PhD Studies: Dr. Jonathan Spencer

7. Chemistry - A European Journal, 2006, 12, 949, Novel Anti-Markovnikov Regioselectivity in the Wacker Reaction of Styrenes

6. J. Org. Chem., 2002, 67, 4627, Convenient Preparation of Pure Trans-Arylalkenes via Palladium Catalyzed Isomerization of the Cis-Alkenes

5. Chem. Comm., 2001, 1844, Evidence that the Availability of an Allylic Hydrogen Governs the Regioselectivity of the Wacker Oxidation

4. Org. Lett., 2001, 3, 25, Derailing the Wacker Oxidation: Development of a New Palladium Catalyzed Alkene Amination Reaction

3. Org. Lett., 2000, 2, 1049, Selective Hydrogenolysis of Novel Benzyl Carbamate Protecting Groups

2. Tetrahedron Lett., 1999, 40, 1803, Preferential Hydrogenolysis of NAP Esters Provides a New Orthogonal Protecting group Strategy for Carboxylic Acids

1. J. Org. Chem., 1998, 63, 4172, Rational Design of Benzyl Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Catalytic Hydrogenolysis

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